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The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

Mammals store metabolic energy as triacylglycerols (TGs) in adipose tissue. TG synthesis is catalyzed by the evolutionarily unrelated acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes DGAT1 and DGAT2, which catalyze the same reaction and account for nearly all TG synthesis. The reasons for thei...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Chitraju, Chandramohan, Walther, Tobias C., Farese, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547635/
https://ncbi.nlm.nih.gov/pubmed/30936184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M093112
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