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The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

Mammals store metabolic energy as triacylglycerols (TGs) in adipose tissue. TG synthesis is catalyzed by the evolutionarily unrelated acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes DGAT1 and DGAT2, which catalyze the same reaction and account for nearly all TG synthesis. The reasons for thei...

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Vydáno v:J Lipid Res
Hlavní autoři: Chitraju, Chandramohan, Walther, Tobias C., Farese, Robert V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547635/
https://ncbi.nlm.nih.gov/pubmed/30936184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M093112
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