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Structure and catalytic mechanism of a human triglyceride synthesis enzyme

Triglycerides (triacylglycerols, TGs) store metabolic energy in organisms and have industrial uses for foods and fuels. Excessive accumulation of TGs in humans causes obesity and is associated with metabolic diseases(1). TG synthesis is catalyzed by acyl-CoA:diacylglycerol acyltransferase (DGAT) enz...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Sui, Xuewu, Wang, Kun, Gluchowski, Nina L., Elliott, Shane D., Liao, Maofu, Walther, Tobias C., Farese, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398557/
https://ncbi.nlm.nih.gov/pubmed/32433611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2289-6
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