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Structure and catalytic mechanism of a human triglyceride synthesis enzyme
Triglycerides (triacylglycerols, TGs) store metabolic energy in organisms and have industrial uses for foods and fuels. Excessive accumulation of TGs in humans causes obesity and is associated with metabolic diseases(1). TG synthesis is catalyzed by acyl-CoA:diacylglycerol acyltransferase (DGAT) enz...
Enregistré dans:
| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398557/ https://ncbi.nlm.nih.gov/pubmed/32433611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2289-6 |
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