Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by aberrant amyloid-β (Aβ) and hyperphosphorylated tau aggregation. We have previously investigated the involvement of SEPTIN family members in AD-related cellular processes and discovered a role for SEPTIN8 in the sorting and acc...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Marttinen, Mikael, Ferreira, Catarina B., Paldanius, Kaisa M. A., Takalo, Mari, Natunen, Teemu, Mäkinen, Petra, Leppänen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696542/
https://ncbi.nlm.nih.gov/pubmed/33203136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112482
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