Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by aberrant amyloid-β (Aβ) and hyperphosphorylated tau aggregation. We have previously investigated the involvement of SEPTIN family members in AD-related cellular processes and discovered a role for SEPTIN8 in the sorting and acc...

詳細記述

保存先:
書誌詳細
出版年:Cells
主要な著者: Marttinen, Mikael, Ferreira, Catarina B., Paldanius, Kaisa M. A., Takalo, Mari, Natunen, Teemu, Mäkinen, Petra, Leppänen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696542/
https://ncbi.nlm.nih.gov/pubmed/33203136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112482
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