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PXR and 4β-Hydroxycholesterol Axis and the Components of Metabolic Syndrome

Pregnane X receptor (PXR) activation has been found to regulate glucose and lipid metabolism and affect obesity in response to high-fat diets. PXR also modulates vascular tone. In fact, PXR appears to regulate multiple components of metabolic syndrome. In most cases, the effect of PXR action is harm...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Hukkanen, Janne, Hakkola, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696146/
https://ncbi.nlm.nih.gov/pubmed/33182477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112445
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