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Serum 4β-hydroxycholesterol increases during fluconazole treatment
PURPOSE: The antifungal drugs ketoconazole and itraconazole reduce serum concentrations of 4β-hydroxycholesterol, which is a validated marker for hepatic cytochrome P450 (CYP) 3A4 activity. We tested the effect of another antifungal triazole agent, fluconazole, on serum concentrations of different s...
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| Publicado no: | Eur J Clin Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8032583/ https://ncbi.nlm.nih.gov/pubmed/33201347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-03041-5 |
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