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Significant increase in plasma 4β-hydroxycholesterol concentration in patients after kidney transplantation
Several previous studies have shown that renal failure decreases not only renal elimination but also metabolic clearance of drugs, particularly those metabolized by CYP3A. However, whether recovery of renal function results in recovery of hepatic CYP3A activity remains unknown. In this study, we eva...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735953/ https://ncbi.nlm.nih.gov/pubmed/23833241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P040022 |
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