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Inhibition and induction of CYP enzymes in humans: an update

The cytochrome P450 (CYP) enzyme family is the most important enzyme system catalyzing the phase 1 metabolism of pharmaceuticals and other xenobiotics such as herbal remedies and toxic compounds in the environment. The inhibition and induction of CYPs are major mechanisms causing pharmacokinetic dru...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Hakkola, Jukka, Hukkanen, Janne, Turpeinen, Miia, Pelkonen, Olavi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603454/
https://ncbi.nlm.nih.gov/pubmed/33111191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02936-7
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