Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo

The objective of these investigations was to determine the possible effects of the novel selective estrogen receptor modulator, ospemifene, on cytochrome P450 (CYP)-mediated drug metabolism. Ospemifene underwent testing for possible effects on CYP enzyme activity in human liver microsomes and in iso...

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Bibliografiska uppgifter
Huvudupphovsmän: Turpeinen, Miia, Uusitalo, Jouko, Lehtinen, Terhi, Kailajärvi, Marita, Pelkonen, Olavi, Vuorinen, Jouni, Tapanainen, Pasi, Stjernschantz, Camilla, Lammintausta, Risto, Scheinin, Mika
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Diversity Preservation International (MDPI) 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742231/
https://ncbi.nlm.nih.gov/pubmed/23880855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140714064
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