Effect of renal impairment on the pharmacokinetics of bupropion and its metabolites

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: There is an ongoing debate regarding the effect of renal impairment on CYP related metabolic activities. The possible effect of renal impairment on hepatic CYP2B6 activity, or on bupropion pharmacokinetics in renally impaired subjects without dialysis treatm...

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Detalhes bibliográficos
Main Authors: Turpeinen, Miia, Koivuviita, Niina, Tolonen, Ari, Reponen, Petri, Lundgren, Stefan, Miettunen, Jouko, Metsärinne, Kaj, Rane, Anders, Pelkonen, Olavi, Laine, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000634/
https://ncbi.nlm.nih.gov/pubmed/17335546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02866.x
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