Effect of renal impairment on the pharmacokinetics of bupropion and its metabolites

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: There is an ongoing debate regarding the effect of renal impairment on CYP related metabolic activities. The possible effect of renal impairment on hepatic CYP2B6 activity, or on bupropion pharmacokinetics in renally impaired subjects without dialysis treatm...

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Autors principals: Turpeinen, Miia, Koivuviita, Niina, Tolonen, Ari, Reponen, Petri, Lundgren, Stefan, Miettunen, Jouko, Metsärinne, Kaj, Rane, Anders, Pelkonen, Olavi, Laine, Kari
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2007
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000634/
https://ncbi.nlm.nih.gov/pubmed/17335546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02866.x
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