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Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I

The cytochrome P4502a5 (Cyp2a5) gene is expressed principally in liver and olfactory mucosa. In the present study, the transcriptional mechanisms of hepatocyte-specific expression of Cyp2a5 were studied in mouse primary hepatocytes. The Cyp2a5 5′-flanking region −3033 to +10 was cloned in front of a...

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Bibliografiska uppgifter
Huvudupphovsmän: Ulvila, Johanna, Arpiainen, Satu, Pelkonen, Olavi, Aida, Kaoru, Sueyoshi, Tatsuya, Negishi, Masahiko, Hakkola, Jukka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2004
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133900/
https://ncbi.nlm.nih.gov/pubmed/15115437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040387
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