A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a major cause which hinders patients from the recovery after intra-articular injuries or surgeries. Currently, no effective treatment is available. In this study, we showed that inhibition of the acute stage chondrocyte death is a promising strategy to mitigat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saito, Motoo, Nishitani, Kohei, Ikeda, Hanako O., Yoshida, Shigeo, Iwai, Sachiko, Ji, Xiang, Nakahata, Akihiro, Ito, Akira, Nakamura, Shinichiro, Kuriyama, Shinichi, Yoshitomi, Hiroyuki, Murata, Koichi, Aoyama, Tomoki, Ito, Hiromu, Kuroki, Hiroshi, Kakizuka, Akira, Matsuda, Shuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695735/
https://ncbi.nlm.nih.gov/pubmed/33247195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77735-2
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