A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a major cause which hinders patients from the recovery after intra-articular injuries or surgeries. Currently, no effective treatment is available. In this study, we showed that inhibition of the acute stage chondrocyte death is a promising strategy to mitigat...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Saito, Motoo, Nishitani, Kohei, Ikeda, Hanako O., Yoshida, Shigeo, Iwai, Sachiko, Ji, Xiang, Nakahata, Akihiro, Ito, Akira, Nakamura, Shinichiro, Kuriyama, Shinichi, Yoshitomi, Hiroyuki, Murata, Koichi, Aoyama, Tomoki, Ito, Hiromu, Kuroki, Hiroshi, Kakizuka, Akira, Matsuda, Shuichi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695735/
https://ncbi.nlm.nih.gov/pubmed/33247195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77735-2
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