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Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity

Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44(High) glioblastoma stem cells and...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Kang, Dong Woo, Hwang, Won Chan, Noh, Yu Na, Park, Kang Seo, Min, Do Sik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693208/
https://ncbi.nlm.nih.gov/pubmed/32725633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5519
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