Phospholipase D1 is upregulated by vorinostat and confers resistance to vorinostat in glioblastoma

Glioblastoma (GBM) is an aggressive brain tumor and drug resistance remains a major barrier for therapeutics. Epigenetic alterations are implicated in GBM pathogenesis, and epigenetic modulators including histone deacetylase (HDAC) inhibitors are exploited as promising anticancer therapies. Here, we...

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Опубликовано в: :J Cell Physiol
Главные авторы: Kang, Dong Woo, Hwang, Won Chan, Noh, Yu Na, Kang, Youra, Jang, Younghoon, Kim, Jung‐Ae, Min, Do Sik
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Original Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692931/
https://ncbi.nlm.nih.gov/pubmed/32869317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29882
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