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Targeting of Phospholipase D1 Ameliorates Collagen-Induced Arthritis via Modulation of Treg and Th17 Cell Imbalance and Suppression of Osteoclastogenesis

Phospholipase D1 (PLD1) plays a crucial role in various inflammatory and autoimmune diseases. Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease. However, the role of PLD1 in the pathogenesis of RA remains unknown. Here, we first investigated the role and effects of PLD1 in colla...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Yoo, Hyun Jung, Hwang, Won Chan, Min, Do Sik
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247592/
https://ncbi.nlm.nih.gov/pubmed/32370217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093230
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