Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase D (PLD) isozymes are dysregulated in various cancers. Recently, we reported th...

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Publicat a:Exp Mol Med
Autors principals: Hwang, Won Chan, Kim, Mi Kyoung, Song, Ju Hyun, Choi, Kang-Yell, Min, Do Sik
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274395/
https://ncbi.nlm.nih.gov/pubmed/25475140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.74
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