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Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity
Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44(High) glioblastoma stem cells and...
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| Veröffentlicht in: | J Pathol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7693208/ https://ncbi.nlm.nih.gov/pubmed/32725633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5519 |
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