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Hetero‐Diels–Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform

We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of hetero‐Diels–Alder cycloaddition through their inherent terminal thiocarbonylthio moiety with a diene‐modified model protein. Quantitative conjugation occurs over the...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Beloqui, Ana, Mane, Shivshankar R., Langer, Marcel, Glassner, Mathias, Bauer, Dennis M., Fruk, Ljiljana, Barner‐Kowollik, Christopher, Delaittre, Guillaume
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693046/
https://ncbi.nlm.nih.gov/pubmed/32729643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005747
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