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Hetero‐Diels–Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform

We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of hetero‐Diels–Alder cycloaddition through their inherent terminal thiocarbonylthio moiety with a diene‐modified model protein. Quantitative conjugation occurs over the...

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Foilsithe in:Angew Chem Int Ed Engl
Main Authors: Beloqui, Ana, Mane, Shivshankar R., Langer, Marcel, Glassner, Mathias, Bauer, Dennis M., Fruk, Ljiljana, Barner‐Kowollik, Christopher, Delaittre, Guillaume
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693046/
https://ncbi.nlm.nih.gov/pubmed/32729643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005747
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