Hetero‐Diels–Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform

We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of hetero‐Diels–Alder cycloaddition through their inherent terminal thiocarbonylthio moiety with a diene‐modified model protein. Quantitative conjugation occurs over the...

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Библиографические подробности
Опубликовано в: :Angew Chem Int Ed Engl
Главные авторы: Beloqui, Ana, Mane, Shivshankar R., Langer, Marcel, Glassner, Mathias, Bauer, Dennis M., Fruk, Ljiljana, Barner‐Kowollik, Christopher, Delaittre, Guillaume
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693046/
https://ncbi.nlm.nih.gov/pubmed/32729643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005747
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