Hetero‐Diels–Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform

We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of hetero‐Diels–Alder cycloaddition through their inherent terminal thiocarbonylthio moiety with a diene‐modified model protein. Quantitative conjugation occurs over the...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Beloqui, Ana, Mane, Shivshankar R., Langer, Marcel, Glassner, Mathias, Bauer, Dennis M., Fruk, Ljiljana, Barner‐Kowollik, Christopher, Delaittre, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693046/
https://ncbi.nlm.nih.gov/pubmed/32729643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005747
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