Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target

Tau plays an important pathological role in a group of neurodegenerative diseases called tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic encephalopathy and corticobasal degeneration. In each disease, tau self-assembles abnormally to form filaments that deposit...

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Detalles Bibliográficos
Publicado en:Front Neurol
Main Authors: Oakley, Sebastian S., Maina, Mahmoud B., Marshall, Karen E., Al-Hilaly, Youssra K., Harrington, Charlie R., Wischik, Claude M., Serpell, Louise C.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Neurology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688747/
https://ncbi.nlm.nih.gov/pubmed/33281730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.590754
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