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A pharmacokinetic‐pharmacodynamic study of a single dose of febuxostat in healthy subjects
AIMS: To examine the pharmacokinetic‐phamacodynamic (PK‐PD) relationships of plasma febuxostat and serum urate and the effect of a single dose of the drug on renal excretion and fractional clearance of urate (FCU). METHODS: Blood and urine samples were collected at baseline and up to 145 hours follo...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7688545/ https://ncbi.nlm.nih.gov/pubmed/32386239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14357 |
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