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Effect of food or antacid on pharmacokinetics and pharmacodynamics of febuxostat in healthy subjects
AIMS: To evaluate the effects of food or antacid on the pharmacokinetics and/or pharmacodynamics of febuxostat. METHODS: Four Phase I, two-period, crossover studies were performed in healthy male and female subjects. Subjects either received single 40-mg (n = 24), multiple 80-mg (n = 24) and single...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291255/ https://ncbi.nlm.nih.gov/pubmed/17953718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03016.x |
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