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Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites
BACKGROUND: The complex composition of different cell types within a tissue can be estimated by deconvolution of bulk gene expression profiles or with various single-cell sequencing approaches. Alternatively, DNA methylation (DNAm) profiles have been used to establish an atlas for multiple human tis...
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| Veröffentlicht in: | BMC Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7687708/ https://ncbi.nlm.nih.gov/pubmed/33234153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00910-4 |
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