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Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites

BACKGROUND: The complex composition of different cell types within a tissue can be estimated by deconvolution of bulk gene expression profiles or with various single-cell sequencing approaches. Alternatively, DNA methylation (DNAm) profiles have been used to establish an atlas for multiple human tis...

詳細記述

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書誌詳細
出版年:BMC Biol
主要な著者: Schmidt, Marco, Maié, Tiago, Dahl, Edgar, Costa, Ivan G., Wagner, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687708/
https://ncbi.nlm.nih.gov/pubmed/33234153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00910-4
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