DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy

DNA-methylation (DNAm) levels at age-associated CpG sites can be combined into epigenetic aging signatures to estimate donor age. It has been demonstrated that the difference between such epigenetic age-predictions and chronological age is indicative for of all-cause mortality in later life. In this...

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Publicado en:Aging (Albany NY)
Autores principales: Lin, Qiong, Weidner, Carola I., Costa, Ivan G., Marioni, Riccardo E., Ferreira, Marcelo R. P., Deary, Ian J., Wagner, Wolfgang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789590/
https://ncbi.nlm.nih.gov/pubmed/26928272
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