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CD4(+) T Cell Help Selectively Enhances High Avidity Tumor Antigen-Specific CD8(+) T Cells
Maintaining anti-tumor immunity remains a persistent impediment to cancer immunotherapy. We and others have previously reported that high avidity CD8(+) T cells are more susceptible to tolerance induction in the tumor microenvironment. In the current study, we used a novel model where T cells derive...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7687044/ https://ncbi.nlm.nih.gov/pubmed/26320256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401571 |
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