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Avidity maturation of memory CD8 T cells is limited by self-antigen expression

Immune tolerance to self-antigens is a complex process that utilizes multiple mechanisms working in concert to maintain homeostasis and prevent autoimmunity. We developed a system that revealed a population of self-specific CD8 T cells within the endogenous T cell repertoire. Immunization of ovalbum...

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Detaylı Bibliyografya
Asıl Yazarlar: Turner, Michael J., Jellison, Evan R., Lingenheld, Elizabeth G., Puddington, Lynn, Lefrançois, Leo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525599/
https://ncbi.nlm.nih.gov/pubmed/18625745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072390
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