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Avidity maturation of memory CD8 T cells is limited by self-antigen expression
Immune tolerance to self-antigens is a complex process that utilizes multiple mechanisms working in concert to maintain homeostasis and prevent autoimmunity. We developed a system that revealed a population of self-specific CD8 T cells within the endogenous T cell repertoire. Immunization of ovalbum...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525599/ https://ncbi.nlm.nih.gov/pubmed/18625745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072390 |
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