Distinct mechanisms mediate naïve and memory CD8 T-cell tolerance

Peripheral tolerance to developmentally regulated antigens is necessary to sustain tissue homeostasis. We have now devised an inducible and reversible system that allows interrogation of T-cell tolerance induction in endogenous naïve and memory CD8 T cells. Our data show that peripheral CD8 T-cell t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jellison, Evan R., Turner, Michael J., Blair, David A., Lingenheld, Elizabeth G., Zu, Li, Puddington, Lynn, Lefrançois, Leo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535649/
https://ncbi.nlm.nih.gov/pubmed/23236165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217409110
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