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Distinct mechanisms mediate naïve and memory CD8 T-cell tolerance
Peripheral tolerance to developmentally regulated antigens is necessary to sustain tissue homeostasis. We have now devised an inducible and reversible system that allows interrogation of T-cell tolerance induction in endogenous naïve and memory CD8 T cells. Our data show that peripheral CD8 T-cell t...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535649/ https://ncbi.nlm.nih.gov/pubmed/23236165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217409110 |
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