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Endogenous Naive CD8(+) T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection
Through genetic recombination, the adaptive immune system generates a diverse T cell repertoire allowing recognition of a vast spectrum of foreign antigens. Any given CD8(+) T cell specificity is thought to be rare, but none have been directly quantified. Here, major histocompatibility complex tetra...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2008
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836785/ https://ncbi.nlm.nih.gov/pubmed/18499487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.04.010 |
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