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Endogenous Naive CD8(+) T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

Through genetic recombination, the adaptive immune system generates a diverse T cell repertoire allowing recognition of a vast spectrum of foreign antigens. Any given CD8(+) T cell specificity is thought to be rare, but none have been directly quantified. Here, major histocompatibility complex tetra...

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書誌詳細
主要な著者: Obar, Joshua J., Khanna, Kamal M., Lefrançois, Leo
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836785/
https://ncbi.nlm.nih.gov/pubmed/18499487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.04.010
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