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Early events governing memory CD8(+) T-cell differentiation

Understanding the regulation of the CD8(+) T-cell response and how protective memory cells are generated has been intensely studied. It is now appreciated that a naive CD8(+) T cell requires at least three signals to mount an effective immune response: (i) TCR triggering, (ii) co-stimulation and (ii...

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Библиографические подробности
Главные авторы: Obar, Joshua J., Lefrançois, Leo
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908475/
https://ncbi.nlm.nih.gov/pubmed/20504887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq053
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