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Pathogen induced inflammatory environment controls effector and memory CD8(+) T cell differentiation()
In response to infection CD8(+) T cells integrate multiple signals and undergo an exponential increase in cell numbers. Simultaneously, a dynamic differentiation process occurs, resulting in the formation of short-lived (SLEC; CD127(low)KLRG1(high)) and memory-precursor (MPEC; CD127(high)KLRG1(low))...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208080/ https://ncbi.nlm.nih.gov/pubmed/21987662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102335 |
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