Glycosaminoglycan Compositional Analysis of Relevant Tissues in Zika Virus Pathogenesis and in Vitro Evaluation of Heparin as an Antiviral against Zika Virus Infection

Zika virus (ZIKV) is an enveloped RNA virus from the flavivirus family that can cause fetal neural abnormalities in pregnant women. Previously, we established that ZIKV-EP (envelope protein) binds to human placental chondroitin sulfate (CS), suggesting that CS may be a potential host cell surface re...

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Pubblicato in:Biochemistry
Autori principali: Kim, So Young, Koetzner, Cheri A., Payne, Anne F., Nierode, Gregory J., Yu, Yanlei, Wang, Rufeng, Barr, Evan, Dordick, Jonathan S., Kramer, Laura D., Zhang, Fuming, Linhardt, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686953/
https://ncbi.nlm.nih.gov/pubmed/30698412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01267
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