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Enzymatic Synthesis of Glycosaminoglycan Heparin

Heparin and its low molecular weight heparin derivatives, widely used as clinical anticoagulants, are acidic polysaccharide members of a family of biomacromolecules called glycosaminoglycans (GAGs). Heparin and the related heparan sulfate are biosynthesized in the Golgi apparatus of eukaryotic cells...

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Bibliographic Details
Main Authors: Linhardt, Robert J., Dordick, Jonathan S., Deangelis, Paul L., Liu, Jian
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140616/
https://ncbi.nlm.nih.gov/pubmed/17629842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-2007-982076
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