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Preparation and application of a “clickable” acceptor for enzymatic synthesis of heparin oligosaccharides

A “clickable” disaccharide was prepared by treating the aldehyde precursor with hydroxylamine, followed by the catalytic hydrogenation and diazotransfer reaction. This disaccharide was successfully applied to the elongation of the backbone construction of ultralow molecular weight (ULMW) heparins us...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cai, Chao, Edgar, Kristi, Liu, Jian, Linhardt, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638765/
https://ncbi.nlm.nih.gov/pubmed/23524108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2013.02.010
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