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Preparation and application of a “clickable” acceptor for enzymatic synthesis of heparin oligosaccharides
A “clickable” disaccharide was prepared by treating the aldehyde precursor with hydroxylamine, followed by the catalytic hydrogenation and diazotransfer reaction. This disaccharide was successfully applied to the elongation of the backbone construction of ultralow molecular weight (ULMW) heparins us...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638765/ https://ncbi.nlm.nih.gov/pubmed/23524108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2013.02.010 |
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