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Molecular Mass Characterization of Glycosaminoglycans with Different Degrees of Sulfation in Bioengineered Heparin Process by Size Exclusion Chromatography

Different degrees of glycosaminoglycan sulfation result in their different charge densities. The charge density differences impact their migration behavior in polyacrylamide gel electrophoresis and size exclusion chromatography, two of the most common methods for determining relative molecular masse...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Zhenyu, Zhang, Fuming, Dordick, Jonathan S., Linhardt, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525092/
https://ncbi.nlm.nih.gov/pubmed/23258975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157341112803216753
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