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Molecular Mass Characterization of Glycosaminoglycans with Different Degrees of Sulfation in Bioengineered Heparin Process by Size Exclusion Chromatography

Different degrees of glycosaminoglycan sulfation result in their different charge densities. The charge density differences impact their migration behavior in polyacrylamide gel electrophoresis and size exclusion chromatography, two of the most common methods for determining relative molecular masse...

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Hlavní autoři: Wang, Zhenyu, Zhang, Fuming, Dordick, Jonathan S., Linhardt, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525092/
https://ncbi.nlm.nih.gov/pubmed/23258975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157341112803216753
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