Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-associated Virus

Adeno-associated virus (AAV) is a key candidate in the development of gene therapy. In this report, we used surface plasmon resonance spectroscopy to study the interaction between AAV and heparin and other glycosaminoglycans. Surface plasmon resonance results revealed that heparin binds to AAV with...

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Bibliographic Details
Main Authors: Zhang, Fuming, Aguilera, Javier, Beaudet, Julie M., Xie, Qing, Lerch, Thomas F., Davulcu, Omar, Colón, Wilfredo, Chapman, Michael S., Linhardt, Robert J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859860/
https://ncbi.nlm.nih.gov/pubmed/23952613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008676
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