Dexamethasone and Glucocorticoid-Induced Matrix Temporally Modulate Key Integrins, Caveolins, Contractility, and Stiffness in Human Trabecular Meshwork Cells

PURPOSE: To determine the temporal effects of dexamethasone (DEX) and glucocorticoid-induced matrix (GIM) on integrins/integrin adhesomes, caveolins, cytoskeletal-related proteins, and stiffness in human trabecular meshwork (hTM) cells. METHODS: Primary hTM cells were plated on plastic dishes (TCP),...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Yemanyi, Felix, Baidouri, Hasna, Burns, Alan R., Raghunathan, VijayKrishna
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Glaucoma
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686803/
https://ncbi.nlm.nih.gov/pubmed/33170205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.13.16
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