CXCR7: a β-arrestin-biased receptor that potentiates cell migration and recruits β-arrestin2 exclusively through Gβγ subunits and GRK2

BACKGROUND: Some chemokine receptors referred to as atypical chemokine receptors (ACKRs) are thought to non-signaling decoys because of their inability to activate typical G-protein signaling pathways. CXCR7, also known as ACKR3, binds to only two chemokines, SDF-1α and I-TAC, and recruits β-arresti...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Biosci
Autori principali: Nguyen, Huong Thi, Reyes-Alcaraz, Arfaxad, Yong, Hyo Jeong, Nguyen, Lan Phuong, Park, Hee-Kyung, Inoue, Asuka, Lee, Cheol Soon, Seong, Jae Young, Hwang, Jong-Ik
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686738/
https://ncbi.nlm.nih.gov/pubmed/33292475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00497-x
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