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Does expression of a human complement-regulatory protein on xenograft cells protect them from systemic complement activation? Experimental research

BACKGROUND: There are many causes of systemic complement activation, which may have detrimental effects on a pig xenograft. Transgenic expression of one or more human complement-regulatory proteins (hCRPs), e.g., hCD46, provides some protection to the xenograft, but it is not known whether it protec...

詳細記述

保存先:
書誌詳細
出版年:Int J Surg
主要な著者: Jagdale, Abhijit, Nguyen, Huy Quoc, Li, Juan, Burnette, KaLia, Ayares, David, Cooper, David K.C., Hara, Hidetaka
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686296/
https://ncbi.nlm.nih.gov/pubmed/32987208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijsu.2020.09.034
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