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Does expression of a human complement-regulatory protein on xenograft cells protect them from systemic complement activation? Experimental research
BACKGROUND: There are many causes of systemic complement activation, which may have detrimental effects on a pig xenograft. Transgenic expression of one or more human complement-regulatory proteins (hCRPs), e.g., hCD46, provides some protection to the xenograft, but it is not known whether it protec...
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| Publicado no: | Int J Surg |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7686296/ https://ncbi.nlm.nih.gov/pubmed/32987208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijsu.2020.09.034 |
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