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Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation

Triple-knockout (TKO) pigs may be ideal sources of organs for clinical xenotransplantation because many humans have no preformed antibody to TKO pig cells. Intravenous immunoglobulin (IVIg) is widely used for severe infection or the treatment/prevention of antibody-mediated rejection in allotranspla...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yamamoto, Takayuki, Cui, Yehua, Patel, Diyan, Jagdale, Abhijit, Iwase, Hayato, Ayares, David, Cooper, David K. C., Hara, Hidetaka
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367287/
https://ncbi.nlm.nih.gov/pubmed/32678137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68505-1
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