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Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation

Triple-knockout (TKO) pigs may be ideal sources of organs for clinical xenotransplantation because many humans have no preformed antibody to TKO pig cells. Intravenous immunoglobulin (IVIg) is widely used for severe infection or the treatment/prevention of antibody-mediated rejection in allotranspla...

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Publicat a:Sci Rep
Autors principals: Yamamoto, Takayuki, Cui, Yehua, Patel, Diyan, Jagdale, Abhijit, Iwase, Hayato, Ayares, David, Cooper, David K. C., Hara, Hidetaka
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367287/
https://ncbi.nlm.nih.gov/pubmed/32678137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68505-1
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